In partnership with

Teams

Immuno-inflammatory Diseases

During the past decade, novel revolutionary frontiers have been opened at the immuno-inflammatory research fields. Indeed, with the help of modern, state-of-the-art technologies (immunomics and other omics, systems biology) it was identified that the immune system is much more complex than previously thought and that its proper functions are defined by multi-directional intercellular communications between cellular (and humoral) components of innate and adaptive immunity.

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Edit Buzás MD, PhD, DSc

VIDEO INTRODUCTION >

Prof. Dr. András Dinnyés

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Balázs Enyedi MD, PhD

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Prof. Lajos Kemény MD

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Bálint Kintses PhD

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József Maléth MD, PhD

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Metabolic and Cardiovascular Diseases

Metabolic and cardiovascular (CV) diseases are among the major cause of death in Hungary and worldwide, thus impose an enormous social and economic burden. In the clinical practice there is a great need for i) the elucidation of the molecular pathomechanism of such high-burden diseases (including obesity, diabetes, heart failure), as well as for ii) the development of novel therapies, cost-effective treatments and iii) more personalized or at least targeted therapeutic approaches.

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László Csanády MD, PhD, DSc

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Balázs Papp PhD

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Zoltán Varga MD, PhD

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Genomic Instability and Cancer

In the EU-28, cancer accounts for 25.8% of the total number of deaths, acquiring the second position behind cardiovascular diseases. In 2012, among the EU member states, the highest standardized death rates for cancer were recorded in Hungary and Croatia, both with rates over 330 per 100 000 inhabitants (EuroStat data). During the past decade(s), significant developments have been made to lower the burdens related to cancer and its complications.

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Antal Berényi MD, PhD

VIDEO INTRODUCTION >

Advanced Core Facilities

A key component of the operational model for HCEMM is the co-development of Advanced Core Facilities (ACFs) aligned with the strengths of the founding institutions. The HCEMM ACF model follows the modus operandi of the EMBL core facilities. The main goal is to optimally support researchers with a high measurement volume and a low error rate, so that the efficiency of HCEMM’s research groups is increased in terms of excellence (output of high-quality scientific papers) and sustainability (ability to generate income by competitive grants, spin-offs and technology transfer agreements). In order to achieve these goals, research groups are encouraged to use the equipment of the ACFs instead of purchasing their own, which results in a more efficient use of resources, avoiding unnecessary duplications and improving the utilization of measurement capacities.

The ACFs presents a range of services tailored to the requirements of HCEMM researchers. Simultaneously, it also serves as an EU-level infrastructural, competence and training base that offers its capacities for any Hungarian and EMBL partner researcher as well as for external users.

The HCEMM ACFs provide clear benefits to researchers, such as:

  • experienced and highly educated staff that can help in setting up and executing experiments
  • large variety of research infrastructure, unaffordable by single research groups
  • infrastructure maintenance and renewal that is covered by contracts with vendors
  • professional user management and pay per system usage

The ACFs serve as a bridge between the research groups involved in technology development and future users who expect to utilize novel technology achievements in their mature form. The ACF network builds on the expertise of research groups, but its advanced technologies will be developed towards streamlining their utilization by a larger userbase. An important focus of the HCEMM is to bring our ACF network into direct contact with research groups and companies developing interesting, applicable technologies.

Our ACFs are established in Szeged and Budapest, so that they provide the best support to the HCEMM founding institutions located in these cities.

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Domokos Máthé DVM PhD

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