The four thematic pillars at the HCEMM are highly complementary and synergistic in terms of the underlying concepts and research approaches. All of them involve the use of high-end technologies and benefit from the established advanced core facilities (ACF). These thematic pillars already have a stronghold in the Hungarian research system, so to establish the HCEMM research areas, already existing excellent Hungarian groups have created a ‘seed incubator environment’ of scientific excellence (research, infrastructure, education).