Genomic Instability and Cancer

Pub

29. GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects.

Kotmayer L, Romero-Moya D, Marin-Bejar O, Kozyra E, Català A, Bigas A, Wlodarski MW, Bödör C, Giorgetti A.
Journal/Proc./Book:
British Journal of Haematology
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
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28. The EHA Research Roadmap: Malignant Lymphoid Diseases.

Dreyling M, André M, Gökbuget N, Tilly H, Jerkeman M, Gribben J, Ferreri A, Morel P, Stilgenbauer S, Fox C, Maria Ribera J, Zweegman S, Aurer I, Bödör C, Burkhardt B, Buske C, Dollores Caballero M, Campo E, Chapuy B, Davies A, de Leval L, Doorduijn J, Federico M, Gaulard P, Gay F, Ghia P, Grønbæk K, Goldschmidt H, Kersten MJ, Kiesewetter B, Landman-Parker J, Le Gouill S, Lenz G, Leppä S, Lopez-Guillermo A, Macintyre E, Mantega MVM, Moreau P, Moreno C, Nadel B, Okosun J, Owen R, Pospisilova S, Pott C, Robak T, Spina M, Stamatopoulos K, Stary J, Tarte K, Tedeschi A, Thieblemont C, Trappe RU, Trümper LH, Salles G.
Journal/Proc./Book:
HemaSphere
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
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27. Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia

Veres T, Voniatis C, Molnár K, Nesztor D, Fehér D, Ferencz A, Gresits I, Thuróczy G, Márkus BG, Simon F, Nemes NM, García-Hernández M, Reiniger L, Horváth I, Máthé D, Szigeti K, Tombácz E, Jedlovszky-Hajdu A.
Journal/Proc./Book:
Pathology&Oncology Research
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
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26. Germline MUTYH mutations and high-grade gliomas: novel evidence for a potential association

Bedics G, Kotmayer L, Zajta E, Hegyi LL, Brückner EÁ, Rajnai H, Reiniger L, Bödör C, Garami M, Scheich B.
Journal/Proc./Book:
Genes Chromosomes and Cancer
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
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Pub

25. Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia

Egyed B, Horváth A, Semsei ÁF, Szalai C, Müller J, Erdélyi DJ, Kovács GT
Journal/Proc./Book:
Pathology and Oncology Research
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
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Pub

24. Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management.

Arndt C, Bergmann R, Striese F, Merkel K, Máthé D, Loureiro LR, Mitwasi N, Kegler A, Fasslrinner F, González Soto KE, Neuber C, Berndt N, Kovács N, Szöllősi D, Hegedűs N, Tóth G, Emmermann J-P, Harikumar KB, Kovacs T, Bachmann M, Feldmann A.
Journal/Proc./Book: C
ancers
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
doi doiicon

Pub

23. Correlations Between the Expression of Stromal Cell Activation Related Biomarkers, L-NGFR, Phospho-ERK1-2 and CXCL12, and Primary Myelofibrosis Progression.

Szekely T, Krenacs T, Maros ME, Bodor C, Daubner V, Csizmadia A, Vrabely B, Timar B.
Journal/Proc./Book:
Pathology&Oncology Research
Year:
2022
Thematic Pillar:
Genomic Instability and Cancer
doi doiicon

Pub

22. A series of xanthenes inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade.

Fenteany G, Sharma G, Gaur P, Borics A, Wéber E, Kiss E, Haracska L.
Journal/Proc./Book:
iScience
Year:
2022
Thematic Pillar: Genomic Instability and Cancer
doi doiicon

Pub

21. Acquired somatic variants in inherited myeloid malignancies.

Armes H, Rio-Machin A, Krizsán S, Bödör C, Kaya F, Bewicke-Copley F, Alnajar J, Walne A, Péterffy B, Tummala H, Rouault-Pierre K, Dokal I, Vulliamy T, Fitzgibbon J.
Journal/Proc./Book: Leukemia
Year: 2022
Thematic Pillar: Genomic Instability and Cancer

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20. The Rad5 helicase and RING domains contribute to genome stability through their independent catalytic activities.

Toth R, Balogh D, Pinter L, Jaksa G, Szeplaki B, Graf A, Gyorfy Z, Zs Enyedi M, Kiss E, Haracska L, Unk I.
Journal/Proc./Book: Journal of molecular biology
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

19. Temporally Targeted Interactions With Pathologic Oscillations as Therapeutical Targets in Epilepsy and Beyond.

Földi T, Lőrincz ML and Berényi
Journal/Proc./Book: Frontiers in Neural Circuits
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

18. Distinct miRNA Expression Signatures of Primary and Secondary Central Nervous System Lymphomas.

Sebestyén E, Nagy Á, Marosvári D, Rajnai H, Kajtár B, Deák B, Matolcsy A, Brandner S, Storhoff J, Chen N, Bagó AG, Bödör C, Reiniger L.
Journal/Proc./Book: The journal of molecular diagnostics
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

17. Single-Cell Sequencing: Biological Insight and Potential Clinical Implications in Pediatric Leukemia

Donát Alpár, Bálint Egyed, Csaba Bödör, Gábor T. Kovács
Journal/Proc./Book: Cancers
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

16. Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovani Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan
Journal/Proc./Book: Nature Communications
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

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15. SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response

Hajnalka Majoros, Barbara N. Borsos, Zsuzsanna Ujfaludi, Zoltán G. Páhi, Mónika Mórocz, Lajos Haracska, Imre Miklós Boros, Tibor Pankotai
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

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14. Nodular fasciitis: a comprehensive, time-correlated investigation of 17 cases

Zoltán Sápi, Zoltán Lippai, Gergő Papp, Lajos Hegyi, Johanna Sápi, Katalin Dezső, Károly Szuhai
Journal/Proc./Book: Modern Pathology
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

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13. Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax

Ambrus Gángó, Richárd Kiss, Péter Farkas, Eid Hanna, Judit Demeter, Beáta Deák, Dóra Lévai, Lili Kotmayer, Donát Alpár, András Matolcsy, Csaba Bödör, Zoltán Mátrai, Botond Timár
Journal/Proc./Book: Pathology
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

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Pub

12. The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies

Yuichi Takeuchi, Anett J. Nagy, Lívia Barcsai, Qun Li, Masahiro Ohsawa, Kenji Mizuseki, Antal Berényi
Journal/Proc./Book: Frontiers in Neural Circuits
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

11. BC-Monitor: Towards a Routinely Accessible Circulating Tumor DNA-Based Tool for Real-Time Monitoring Breast Cancer Progression and Treatment Effectiveness

Katalin Priskin, Sára Pólya, Lajos Pintér, Gábor Jaksa, Bernadett Csányi, Márton Zsolt Enyedi, Eszter Sági-Zsigmond, Farkas Sükösd, Orsolya Oláh-Németh, Gyöngyi Kelemen, Alíz Nikolényi, Gabriella Uhercsák, Dóra Sántha, Ágnes Dobi, Éva Szilágyi, Erzsébet Valicsek, László Tordai, Rozália Tóth, Zsuzsanna Kahán, Lajos Haracska
Journal/Proc./Book: Cancers
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

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Pub

10. Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA

Qiuzhen Li, Kata Dudás, Gabriella Tick, Lajos Haracska
Journal/Proc./Book: Frontiers in Cell and Developmental Biology
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

9. The RUNX1 Database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy

Claire C. Homan, Sarah L. King-Smith, David M. Lawrence, Peer Arts, Jinghua Feng, James Andrews, Mark Armstrong, Thuong Ha, Julia Dobbins, Michael W. Drazer, Kai Yu, Csaba Bödör, Alan Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Jude Fitzgibbon, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V. Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Rienhoff, Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Velloso, Benedict Yan, Paul Liu, Lucy A. Godley, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Anna L. Brown
Journal/Proc./Book: Haematologica
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

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8. The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

Marcela B. Mansur, Caroline L. Furness, Sirintra Nakjang, Amir Enshaei, Donat Alpar, Sue M. Colman, Lynne Minto, Julie Irving, Beth V. Poole, Elda P. Noronha, Suvi Savola, Sameena Iqbal, John Gribben, Maria S. Pombo‐de‐Oliveira, Tony M. Ford, Mel F. Greaves, Frederik W. Delft
Journal/Proc./Book: Cancer Medicine
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

7. The Combination of Single-Cell and Next-Generation Sequencing Can Reveal Mosaicism for BRCA2 Mutations and the Fine Molecular Details of Tumorigenesis

Alexandra Gráf, Márton Zsolt Enyedi, Lajos Pintér, Éva Kriston-Pál, Gábor Jaksa, Árpád Bálind, Éva Ezer, Péter Horváth, Farkas Sükösd, Ernő Kiss, Lajos Haracska
Journal/Proc./Book: Cancers
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

6. Screening and monitoring of the BTK C481S mutation in a real‐world cohort of patients with relapsed/refractory chronic lymphocytic leukaemia during ibrutinib therapy

Csaba Bödör, Lili Kotmayer, Tamás László, Ferenc Takács, Gábor Barna, Richárd Kiss, Endre Sebestyén, Tibor Nagy, Lajos László Hegyi, Gábor Mikala, Sándor Fekete, Péter Farkas, Alexandra Balogh, Tamás Masszi, Judit Demeter, Júlia Weisinger, Hussain Alizadeh, Béla Kajtár, Zoltán Kohl, Róbert Szász, Lajos Gergely, Timea Gurbity Pálfi, Adrienn Sulák, Balázs Kollár, Miklós Egyed, Márk Plander, László Rejtő, László Szerafin, Péter Ilonczai, Péter Tamáska, Piroska Pettendi, Dóra Lévai, Tamás Schneider, Anna Sebestyén, Péter Csermely, András Matolcsy, Zoltán Mátrai, Donát Alpár
Journal/Proc./Book: British Journal of Haematology
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

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5. Reduced MC4R signaling alters nociceptive thresholds associated with red hair

Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis, Gabor Kozak, Yuichi Takeuchi, Shiqian Shen, Antal Berenyi, Jianren Mao, Clifford J. Woolf, David E. Fisher
Journal/Proc./Book: Science Advances
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases,Genomic Instability and Cancer

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4. Closed-loop stimulation of the medial septum terminates epileptic seizures

Yuichi Takeuchi, Márk Harangozó, Lizeth Pedraza, Tamás Földi, Gábor Kozák, Qun Li, Antal Berényi
Journal/Proc./Book: Brain
Year: 2021
Thematic Pillar: Genomic Instability and Cancer

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Pub

3. Oscillotherapeutics – Time-targeted interventions in epilepsy and beyond

Yuichi Takeuchi, Antal Berényi
Journal/Proc./Book: Neuroscience Research
Year: 2019
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

2. Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss, Lajos Haracska
Journal/Proc./Book: BMC Molecular and Cell Biology
Year: 2020
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

Pub

1. Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism

Gabriel Fenteany, Paras Gaur, Lili Hegedűs, Kata Dudás, Ernő Kiss, Edit Wéber, László Hackler, Tamás Martinek, László G. Puskás, Lajos Haracska
Journal/Proc./Book: Scientific Reports
Year: 2019
Thematic Pillar: Genomic Instability and Cancer

doi doiicon

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