Immuno-inflammatory Diseases

106. Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration.

Garza AP, Morton L, Pállinger É, Buzás EI, Schreiber S, Schott BH, Dunay IR.
Journal/Proc./Book: Brain, Behaviour, and Immunity
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases

105. Spinocerebellar Ataxia in a Hungarian Female Patient with a Novel Variant of Unknown Significance in the CCDC88C Gene.

Boros FA, Szpisjak L, Bozó R, Kelemen E, Zádori D, Salamon A, Danis J, Kalmár T, Maróti Z, Molnár MJ, Klivényi P, Széll M, Ádám É.
Journal/Proc./Book: International Journal of Molecular Sciences
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases

104. Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains.

Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B.
Journal/Proc./Book: Nature Microbiology
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases, Metabolic and Cardiovascular Diseases

103. Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges of absence seizures.

Atherton Z, Nagy O, Barcsai L, Sere P, Zsigri N, Földi T, Gellért L, Berényi A, Crunelli V, Lőrincz ML.
Journal/Proc./Book: Neurobiology of Disease
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases

102. The Wisdom in Teeth: Neuronal Differentiation of Dental Pulp Cells.

Sramkó B, Földes A, Kádár K, Varga G, Zsembery Á, Pircs K.

Journal/Proc./Book: Cellular Reprogramming
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases

101. Plasticity and stereotypic rewiring of the transcriptome upon bacterial evolution of antibiotic resistance.

Grézal G, Spohn R, Méhi O, Dunai A, Lázár V, Bálint B, Nagy I, Pál C, Papp B.

Journal/Proc./Book: Molecular Biology and Evolution
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases, Metabolic and Cardiovascular Diseases

100. Thiopurines impair the apical plasma membrane expression of CFTR in pancreatic ductal cells via RAC1 inhibition.

Tél B, Papp N, Varga Á, Szabó V, Görög M, Susánszki P, Crul T, Kis A, Sendstad IH, Bagyánszki M, Bódi N, Hegyi P, Maléth J, Pallagi P.
Journal/Proc./Book: Cellular and Molecular Life Sciences
Year: 2023
Thematic Pillar: Immuno Inflammatory Diseases

99. Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility

White R, Sotillo J, Ancarola ME, Borup A, Boysen AT, Brindley PJ, Buzás EI, Cavallero S, Chaiyadet S, Chalmers IW, Cucher MA, Dagenais M, Davis CN, Devaney E, Duque-Correa MA, Eichenberger RM, Fontenla S, Gasan TA, Hokke CH, Kosanovic M, Kuipers ME, Laha T, Loukas A, Maizels RM, Marcilla A, Mazanec H, Morphew RM, Neophytou K, Nguyen LT, Nolte-‘t Hoen E, Povelones M, Robinson MW, Rojas A, Schabussova I, Smits HH, Sungpradit S, Tritten L, Whitehead B, Zakeri A, Nejsum P, Buck AH, Hoffmann KF.
Journal/Proc./Book: Journal of Extracellular Vesicles
Year: 2023
Thematic Pillar: Immuno Inflammatory Diseases

98. Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells

Jennings P, Carta G, Singh P, da Costa Pereira D, Feher A, Dinnyes A, Exner TE, Wilmes A.
Journal/Proc./Book: Cell Biology and Toxicology
Year: 2022
Thematic Pillar: Immuno Inflammatory Diseases

97. Nanofiber formation as a promising technology for preservation and easy storage of extracellular vesicles

Németh K, Kazsoki A, Visnovitz T, Pinke B, Mészáros L, Buzás EI, Zelkó R.
Journal/Proc./Book: Scientific Reports
Year: 2022
Thematic Pillar:  Immuno Inflammatory Diseases

96. Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.

Gergely TG, Kucsera D, Tóth VE, Kovács T, Sayour NV, Drobni ZD, Ruppert M, Petrovich B, Ágg B, Onódi Z, Fekete N, Pállinger É, Buzás EI, Yousif LI, Meijers WC, Radovits T, Merkely B, Ferdinandy P, Varga ZV.
Journal/Proc./Book: British Journal of Pharmacology
Year: 2022

95.  CD3+/CD56+ NKT-like Cells Show Imbalanced Control Immediately after Exercise in Delayed-Onset Muscle Soreness.

Sonkodi B, Pállinger É, Radovits T, Csulak E, Shenker-Horváth K, Kopper B, Buzás EI, Sydó N, Merkely B.
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2022
Thematic Pillar: Immuno Inflammatory Diseases

94. Opportunities and challenges in studying the extracellular vesicle corona.

Buzás EI 
Journal/Proc./Book: Nature Cell Biology
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

93. Extracellular Vesicle-Mediated Metastasis Suppressors NME1 and NME2 Modify Lipid Metabolism in Fibroblasts.

Mátyási B, Petővári G, Dankó T, Butz H, Likó I, Lőw P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnár K, Pálóczi K, Buzás EI, Boissan M, Sebestyén A, Takács-Vellai K.
Journal/Proc./Book:Cancers
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

92. Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles

Valcz G, Újvári B, Buzás EI, Krenács T, Spisák S, Kittel Á, Tulassay Z, Igaz P, Takács I, Molnár B.
Journal/Proc./Book:Frontiers in Oncology
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

91. A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.

Ari E, Vásárhelyi BM, Kemenesi G, Tóth GE, Zana B, Somogyi B, Lanszki Z, Röst G, Jakab F, Papp B, Kintses B.
Journal/Proc./Book: Virus Evolution
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

90. The roles of extracellular vesicles in the immune system.

Buzás EI
Journal/Proc./Book: Nature Reviews Immunology
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

89. Widespread alterations in microRNA biogenesis in human Huntington’s disease putamen.

Petry S, Keraudren R, Nateghi B, Loiselle A, Pircs K, Jakobsson J, Sephton C, Langlois M, St-Amour I, Hébert SS.
Journal/Proc./Book: Acta neuropathologica communications
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

88. A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans.

Bokor E, Ámon J, Varga M, Szekeres A, Hegedűs Z, Jakusch T, Szakonyi Z, Flipphi M, Vágvölgyi C, Gácser A, Scazzocchio C, Hamari Z.
Journal/Proc./Book: Communications Biology
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

87. Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences.

Kovács OT, Tóth E, Ozohanics O, Soltész-Katona E, Marton N, Buzás EI, Hunyady L, Drahos L, Turu G, Nagy G.
Journal/Proc./Book: Frontiers in Immunology
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

86. Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells.

Igaz N, Bélteky P, Kovács D, Papp C, Rónavári A, Szabó D, Gácser A, Kónya Z, Kiricsi M.
Journal/Proc./Book: International Journal of Nanomedicine
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

85. Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis.

Takács T, Németh MT, Bohner F, Vágvölgyi C, Jankovics F, Wilson D, Gácser A.
Journal/Proc./Book: Open Biology
Year: 2022
Thematic Pillar:Immuno Inflammatory Diseases

84. Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter.

Fehér A, Schnúr A, Muenthaisong S, Bellák T, Ayaydin F, Várady G, Kemter E, Wolf E, Dinnyés A.

Journal/Proc./Book: Scientific Reports
Year: 2022
Thematic Pillar: Immuno Inflammatory Diseases

83. Chronic Exposure to the Food Additive tBHQ Modulates Expression of Genes Related to SARS-CoV-2 and Influenza Viruses.

Németh K, Petschner P, Pálóczi K, Fekete N, Pállinger É, Buzás EI, Tamási V.

Journal/Proc./Book: Life
Year: 2022 
Thematic Pillar: Immuno Inflammatory Diseases

82. Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Osteikoetxea X, Silva A, Lázaro-Ibáñez E, Salmond N, Shatnyeva O, Stein J, Schick J, Wren S, Lindgren J, Firth M, Madsen A, Mayr LM, Overman R, Davies R, Dekker N.

Journal/Proc./Book: Extracell Vesicles
Year: 2022
Thematic Pillar: Immuno Inflammatory Diseases

81. Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection.

Sallai I, Marton N, Szatmári A, Kittel Á, Nagy G, Buzás EI, Khamari D, Komlósi Z, Kristóf K, Drahos L, Turiák L, Sugár S, Veres DS, Kendoff D, Zahár Á, Skaliczki G.

Journal/Proc./Book: Public Library of Science

Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

80. Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System In Vitro.

Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, Gacser A, Blasi E, Pericolini E.
Journal/Proc./Book: Microbiology spectrum
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

79. Impaired regulation of PMCA activity by defective CFTR expression promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Madácsy T, Varga Á, Papp N, Tél B, Pallagi P, Szabó V, Kiss A, Fanczal J, Rakonczay Z Jr, Tiszlavicz L, Rázga Z, Hohwieler M, Kleger A, Gray M, Hegyi P, Maléth J

Journal/Proc./Book: Cellular and Molecular Life Sciences
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

78. Hunting Out the autophagic problem in Huntington disease.

Pircs K, Barker RA, Jakobsson J.
Journal/Proc./Book: Autophagy
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

77. Proteome-wide landscape of solubility limits in a bacterial cell.

Györkei Á, Daruka L, Balogh D, Őszi E, Magyar Z, Szappanos B, Fekete G, Fuxreiter M, Horváth P, Pál C, Kintses B, Papp B.
Journal/Proc./Book: Scientific reports
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases, Metabolic and Cardiovascular Diseases

76. Decreased Plasma Level of Cytokeratin 20 (KRT20) Is Indicative of the Emergence and Severity of Acute GvHD Irrespective to the Type of Organ Involvement.

Lupsa N, Szegedi Á, Gézsi A, Vuncs Z, Masszi T, Mikala G, Reményi P, Deola S, Lakshmanan AP, Terranegra A, Buzás EI, Pós Z.
Journal/Proc./Book: Biomedicines
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

75. The effect of antifungal resistance development on the virulence of Candida species.

Bohner F, Papp C, Gácser A.
Journal/Proc./Book: FEMS Yeast Research
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

74. Methods for the identification and characterization of extracellular vesicles in cardiovascular studies – from exosomes to microvesicles.

Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG.
Journal/Proc./Book: Cardiovascular Research
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

73. Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources.

Cillingová A, Tóth R, Mojáková A, Zeman I, Vrzoňová R, Siváková B, Baráth P, Neboháčová M, Klepcová Z, Brázdovič F, Lichancová H, Hodorová V, Brejová B, Vinař T, Mutalová S, Vozáriková V, Mutti G, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J.
Journal/Proc./Book: Plos Genetics
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

72. CD44 Expression Intensity Marks Colorectal Cancer Cell Subpopulations with Different Extracellular Vesicle Release Capacity.

Kelemen A, Carmi I, Seress I, Lőrincz P, Tölgyes T, Dede K, Bursics A, Buzás EI, Wiener Z.
Journal/Proc./Book: International journal of molecular sciences
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

71. Blood-brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells.

Walter FR, Harazin A, Tóth AE, Veszelka S, Santa-Maria AR, Barna L, Kincses A, Biczó G, Balla Z, Kui B, Maléth J, Cervenak L, Tubak V, Kittel Á, Rakonczay Z Jr, Deli MA
Journal/Proc./Book: Fluid and Barrier of the cNS
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

70. Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo.

Vadovics M, Ho J, Igaz N, Alföldi R, Rakk D, Veres É, Szücs B, Horváth M, Tóth R, Szücs A, Csibi A, Horváth P, Tiszlavicz L, Vágvölgyi C, Nosanchuk JD, Szekeres A, Kiricsi M, Henley-Smith R, Moyes DL, Thavaraj S, Brown R, Puskás LG, Naglik JR, Gácser A.
Journal/Proc./Book: mBio
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

69. Regulation of Orai channels by intracellular pH: one step closer to understand CRAC channel biology? J Physiol.

Maléth J.
Journal/Proc./Book: Journal of Physiology
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

68. Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells. Front Mol Neurosci

Francistiová L, Vörös K, Lovász Z, Dinnyés A, Kobolák J.
Journal/Proc./Book: Frontiers in molecular neuroscience
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

67. Bile acid- and ethanol-mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis.

Pallagi P, Görög M, Papp N, Madácsy T, Varga Á, Crul T, Szabó V, Molnár M, Dudás K, Grassalkovich A, Szederkényi E, Lázár G, Venglovecz V, Hegyi P, Maléth J.
Journal/Proc./Book: The journal of physiology A publication of the Physiological Society.
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

66. Transcriptional Analysis-Based Alterations Affecting Neuritogenesis of the Peripheral Nervous System in Psoriasis

Romhányi D, Szabó K, Kemény L, Sebestyén E, Groma G.
Journal/Proc./Book: MDPI Life
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

65. Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements

Mitrečić D, Hribljan V, Jagečić D, Isaković J, Lamberto F, Horánszky A, Zana M, Foldes G, Zavan B, Pivoriūnas A, Martinez S, Mazzini L, Radenovic L, Milasin J, Chachques JC, Buzanska L, Song MS, Dinnyés A.
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

64. Circulating cardiomyocyte-derived extracellular vesicles reflect cardiac injury during systemic inflammatory response syndrome in mice.

Hegyesi H, Pallinger É, Mecsei S, Hornyák B, Kovácsházi C, Brenner GB, Giricz Z, Pálóczi K, Kittel Á, Tóvári J, Turiak L, Khamari D, Ferdinandy P, Buzás EI.
Journal/Proc./Book: Cellular and Molecular Life Sciences
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

63. Psoriasis-Associated Inflammatory Conditions Induce IL-23 mRNA Expression in Normal Human Epidermal Keratinocytes.

Kelemen E, Ádám É, Sági SM, Göblös A, Kemény L, Bata-Csörgő Z, Széll M, Danis J.
Journal/Proc./Book: MDPI- Journal of molecular sciences
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases

62. Erratum to: P459 Expression of SerpinE1, a potential new disease activity marker, reflects therapeutic response in Inflammatory Bowel Disease.

Jójárt B, Molnàr T, Szabó V, Varga Á, Resàl T, Szàntó K, Kata D, Földesi I, Molnár T, Maléth J, Farkas K.
Journal/Proc./Book: Journal of Chron’s and colitis
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

61. Deep Proteomic Analysis on Biobanked Paraffine-Archived Melanoma with Prognostic/Predictive Biomarker Read-Out.

Szadai L, Velasquez E, Szeitz B, Almeida NPd, Domont G, Betancourt LH, Gil J, Marko-Varga M, Oskolas H, Jánosi ÁJ, Boyano-Adánez MdC, Kemény L, Baldetorp B, Malm J, Horvatovich P, Szász AM, Németh IB, Marko-Varga G.
Journal/Proc./Book: Cancers
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

60. Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB1) Receptor

Viktória B. Horváth, Eszter Soltész-Katona, Éva Wisniewski, Anikó Rajki, Eszter Halász, Balázs Enyedi, László Hunyady, András Dávid Tóth, Gergő Szanda
Journal/Proc./Book: Frontiers in Endocrinology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

59. Extracellular vesicle release and uptake by the liver under normo- and hyperlipidemia

Krisztina Németh, Zoltán Varga, Dorina Lenzinger, Tamás Visnovitz, Anna Koncz, Nikolett Hegedűs, Ágnes Kittel, Domokos Máthé, Krisztián Szigeti, Péter Lőrincz, Clodagh O’Neill, Róisín Dwyer, Zhonglin Liu, Edit I. Buzás, Viola Tamási
Journal/Proc./Book: Cellular and Molecular Life Sciences
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases,

58. Epigenetic Mechanisms of ART-Related Imprinting Disorders: Lessons from iPSC and Mouse Models

Alex Horánszky, Jessica L. Becker, Melinda Zana, Anne C. Ferguson-Smith, András Dinnyés
Journal/Proc./Book: Genes
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

57. Maternal One-Carbon Metabolism during the Periconceptional Period and Human Foetal Brain Growth: A Systematic Review

Eleonora Rubini, Inge M. M. Baijens, Alex Horánszky, Sam Schoenmakers, Kevin D. Sinclair, Melinda Zana, András Dinnyés, Régine P. M. Steegers-Theunissen, Melek Rousian
Journal/Proc./Book: Genes
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

56. Environmental Alterations during Embryonic Development: Studying the Impact of Stressors on Pluripotent Stem Cell-Derived Cardiomyocytes

Federica Lamberto, Irene Peral-Sanchez, Suchitra Muenthaisong, Melinda Zana, Sandrine Willaime-Morawek, András Dinnyés
Journal/Proc./Book: Genes
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

55. The golden ages of inflammatory skin diseases: skyrocketing developments in the therapy of psoriasis and atopic dermatitis

L. Kemény
Journal/Proc./Book: Journal of the European Academy of Dermatology and Venereology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

54. Virulence Factors and in-Host Selection on Phenotypes in Infectious Probiotic Yeast Isolates (Saccharomyces ‘boulardii’)

Alexandra Imre, Renátó Kovács, Kitti Pázmándi, Dániel Nemes, Ágnes Jakab, Tünde Fekete, Hanna Viktória Rácz, Ilona Dóczi, Ildikó Bácskay, Attila Gácser, Károly Kovács, László Majoros, Zoltán Farkas, István Pócsi, Walter P. Pfliegler
Journal/Proc./Book: Journal of Fungi
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

53. Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster

Katalin Csonka, Zsolt Tasi, Viktor Vedelek, Csaba Vágvölgyi, Rita Sinka, Attila Gácser
Journal/Proc./Book: Virulence
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

52. Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself

Balázs Koncz, Gergő M. Balogh, Benjamin T. Papp, Leó Asztalos, Lajos Kemény, Máté Manczinger
Journal/Proc./Book: Proceedings of the National Academy of Sciences
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

51. Formation of a protein corona on the surface of extracellular vesicles in blood plasma

Eszter Á. Tóth, Lilla Turiák, Tamás Visnovitz, Csaba Cserép, Anett Mázló, Barbara W. Sódar, András I. Försönits, Gábor Petővári, Anna Sebestyén, Zsolt Komlósi, László Drahos, Ágnes Kittel, György Nagy, Attila Bácsi, Ádám Dénes, Yong Song Gho, Katalin É. Szabó‐Taylor, Edit I. Buzás
Journal/Proc./Book: Journal of Extracellular Vesicles
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

50. Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain

Linda Francistiová, Adrián Klepe, Géza Curley, Károly Gulya, András Dinnyés, Kata Filkor
Journal/Proc./Book: Frontiers in Immunology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

49. Phenotypic plasticity of melanocytes derived from human adult skin

Dániel László Vidács, Zoltán Veréb, Renáta Bozó, Lili Borbála Flink, Hilda Polyánka, István Balázs Németh, Szilárd Póliska, Benjamin Tamás Papp, Máté Manczinger, Róbert Gáspár, Seyedmohsen Mirdamadi, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Journal/Proc./Book: Pigment Cell Frontiers in Immunology Melanoma Research
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

48. Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice

Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser
Journal/Proc./Book: mBio
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

47. Editorial: The Role of Nuclear Molecules in the Pathogenesis of Autoimmune Disease

David S. Pisetsky, Reinhard Voll, Edit I. Buzas
Journal/Proc./Book: Frontiers in Immunology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

46. Genetic Investigation of Inverse Psoriasis

Anikó Göblös, Emese Varga, Katalin Farkas, Kristóf Árvai, Lajos Kemény
Journal/Proc./Book: Life
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

45. Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models

Gyöngyvér Orsolya Sándor, András Áron Soós, Péter Lörincz, Lívia Rojkó, Tünde Harkó, Levente Bogyó, Tamás Tölgyes, Attila Bursics, Edit I. Buzás, Judit Moldvay, Zoltán Wiener
Journal/Proc./Book: Frontiers in Cell and Developmental Biology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

44. The psoriatic non-lesional skin: a battlefield of constant fight between susceptibility and protective factors

Evelyn Kelemen, Renáta Bozó, Gergely Groma, Zsuzsanna Bata-Csörgő, Lajos Kemény, Judit Danis, Márta Széll
Journal/Proc./Book: Journal of Investigative Dermatology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

43. Stress-Related Regulation Is Abnormal in the Psoriatic Uninvolved Skin

Renáta Bozó, Judit Danis, Lili Borbála Flink, Dániel László Vidács, Lajos Kemény, Zsuzsanna Bata-Csörgő
Journal/Proc./Book: Life
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

42. Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Máté Manczinger, Balázs Koncz, Gergő Mihály Balogh, Benjamin Tamás Papp, Leó Asztalos, Lajos Kemény, Balázs Papp, Csaba Pál
Journal/Proc./Book: Nature Cancer
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

41. Alcohol in Psoriasis—From Bench to Bedside

Zita Szentkereszty-Kovács, Krisztián Gáspár, Andrea Szegedi, Lajos Kemény, Dóra Kovács, Dániel Törőcsik
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

40. Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells

Panetha Pansri, Phetcharat Phanthong, Nopparat Suthprasertporn, Yindee Kitiyanant, Alisa Tubsuwan, Andras Dinnyes, Julianna Kobolak, Narisorn Kitiyanant
Journal/Proc./Book: PeerJ
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

39. Supraoptimal Iron Nutrition of Brassica napus Plants Suppresses the Iron Uptake of Chloroplasts by Down-Regulating Chloroplast Ferric Chelate Reductase

Máté Sági-Kazár, Helga Zelenyánszki, Brigitta Müller, Barnabás Cseh, Balázs Gyuris, Sophie Z. Farkas, Ferenc Fodor, Brigitta Tóth, Béla Kovács, Anna Koncz, Tamás Visnovitz, Edit I. Buzás, Barbara Bánkúti, Ferenc Bánáti, Kálmán Szenthe and Ádám Solti
Journal/Proc./Book: Frontiers in Plant Science
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

38. TRAF3 and NBR1 both influence the effect of the disease‐causing CYLD(Arg936X) mutation on NF‐κB activity

Judit Danis, Evelyn Kelemen, Neil Rajan, Nikoletta Nagy, Márta Széll, Éva Ádám
Journal/Proc./Book: Experimental Dermatology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

37. Endoplasmic Reticulum‐Plasma Membrane Contact Sites as an Organizing Principle for Compartmentalized Calcium and cAMP Signaling

Tim Crul, József Maléth
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

36. Nod-Like Receptors in Host Defence and Disease at the Epidermal Barrier

Judit Danis, Mark Mellett
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

35. Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

Markus Breunig, Jessica Merkle, Martin Wagner, Michael K. Melzer, Thomas F.E. Barth, Thomas Engleitner, Johannes Krumm, Sandra Wiedenmann, Christian M. Cohrs, Lukas Perkhofer, Gaurav Jain, Jana Krüger, Patrick C. Hermann, Maximilian Schmid, Tamara Madácsy, Árpád Varga, Joscha Griger, Ninel Azoitei, Martin Müller, Oliver Wessely, Pamela G. Robey, Sandra Heller, Zahra Dantes, Maximilian Reichert, Cagatay Günes, Christian Bolenz, Florian Kuhn, József Maléth, Stephan Speier, Stefan Liebau, Bence Sipos, Bernhard Kuster, Thomas Seufferlein, Roland Rad, Matthias Meier, Meike Hohwieler, Alexander Kleger
Journal/Proc./Book: Cell Stem Cell
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

34. Neural stem cells traffic functional mitochondria via extracellular vesicles

Luca Peruzzotti-Jametti, Joshua D. Bernstock, Cory M. Willis, Giulia Manferrari, Rebecca Rogall, Erika Fernandez-Vizarra, James C. Williamson, Alice Braga, Aletta van den Bosch, Tommaso Leonardi, Grzegorz Krzak, Ágnes Kittel, Cristiane Benincá, Nunzio Vicario, Sisareuth Tan, Carlos Bastos, Iacopo Bicci, Nunzio Iraci, Jayden A. Smith, Ben Peacock, Karin H. Muller, Paul J. Lehner, Edit Iren Buzas, Nuno Faria, Massimo Zeviani, Christian Frezza, Alain Brisson, Nicholas J. Matheson, Carlo Viscomi, Stefano Pluchino
Journal/Proc./Book: PLOS Biology
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

33. Reduced MC4R signaling alters nociceptive thresholds associated with red hair

Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis, Gabor Kozak, Yuichi Takeuchi, Shiqian Shen, Antal Berenyi, Jianren Mao, Clifford J. Woolf, David E. Fisher
Journal/Proc./Book: Science Advances
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases,Genomic Instability and Cancer

32. Advances in the optimisation of therapeutic drug monitoring using serum, tissue and faecal anti-tumour necrosis factor concentration in patients with inflammatory bowel disease treated with TNF-α antagonists

Kata Judit Szántó, Tamara Madácsy, Diána Kata, Tamás Ferenci, Mariann Rutka, Anita Bálint, Renáta Bor, Anna Fábián, Ágnes Milassin, Boldizsár Jójárt, Zoltán Szepes, Ferenc Nagy, Tamás Molnár, Imre Földesi, József Maléth Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis, Gabor Kozak, Yuichi Takeuchi, Shiqian Shen, Antal Berenyi, Jianren Mao, Clifford J. Woolf, David E. Fisher Klaudia Farkas
Journal/Proc./Book: Expert Opinion on Biological Therapy
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

31. An implanted device enables in vivo monitoring of extracellular vesicle‐mediated spread of pro‐inflammatory mast cell response in mice

Krisztina V. Vukman, Andrea Ferencz, Daniella Fehér, Krisztina Juhos, Péter Lőrincz, Tamás Visnovitz, Anna Koncz, Krisztina Pálóczi, Gábor Seregélyes, András Försönits, Delaram Khamari, Alicia Galinsoga, László Drahos, Edit I. Buzás
Journal/Proc./Book: Journal of Extracellular Vesicles
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

30. Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Lilla Erdei, Beáta Szilvia Bolla, Renáta Bozó, Gábor Tax, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Journal/Proc./Book: Acta Dermato-Venereologica
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

29. Dry storage of mammalian spermatozoa and cells: state-of-the-art and possible future directions

P. Loi, D. A. Anzalone, L. Palazzese, A. Dinnyés, J. Saragusty, M. Czernik
Journal/Proc./Book: Reproduction, Fertility and Development
Year: 2021
Thematic Pillar: Immuno-inflammatory Diseases

28. Psychological Effects of the COVID-19 Pandemic on Hungarian Adults

Csanád Szabó, Judit Pukánszky, Lajos Kemény
Journal/Proc./Book: International Journal of Environmental Research and Public Health
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

27. Could basement membrane alterations, resembling micro‐wounds at the dermo‐epidermal junction in psoriatic non‐lesional skin, make the skin susceptible to lesion formation?

Renáta Bozó, Lili Borbála Flink, Nóra Belső, Barbara Gubán, Márta Széll, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Journal/Proc./Book: Experimental Dermatology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

26. Grafted human induced pluripotent stem cells improve the outcome of spinal cord injury: modulation of the lesion microenvironment

Tamás Bellák, Zoltán Fekécs, Dénes Török, Zsuzsanna Táncos, Csilla Nemes, Zsófia Tézsla, László Gál, Suchitra Polgári, Julianna Kobolák, András Dinnyés, Antal Nógrádi, Krisztián Pajer
Journal/Proc./Book: Scientific Reports
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

25. Bile accelerates carcinogenic processes in pancreatic ductal adenocarcinoma cells through the overexpression of MUC4

Eleonóra Gál, Zoltán Veréb, Lajos Kemény, Dávid Rakk, András Szekeres, Eszter Becskeházi, László Tiszlavicz, Tamás Takács, László Czakó, Péter Hegyi, Viktória Venglovecz
Journal/Proc./Book: Scientific Reports
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

24. Shared extracellular vesicle miRNA profiles of matched ductal pancreatic adenocarcinoma organoids and blood plasma samples show the power of organoid technology

Anikó Zeöld, Gyöngyvér Orsolya Sándor, Anna Kiss, András Áron Soós, Tamás Tölgyes, Attila Bursics, Ákos Szűcs, László Harsányi, Ágnes Kittel, András Gézsi, Edit I. Buzás, Zoltán Wiener
Journal/Proc./Book: Cellular and Molecular Life Sciences
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

23. Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations

Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp
Journal/Proc./Book: Molecular Biology and Evolution
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases,Metabolic and Cardiovascular Diseases

22. Cyclooxygenase-2 Modulates Glycosaminoglycan Production in the Skin During Salt Overload

Róbert Agócs, Domonkos Pap, Dániel Sugár, Gábor Tóth, Lilla Turiák, Zoltán Veréb, Lajos Kemény, Tivadar Tulassay, Ádám Vannay, Attila J. Szabó
Journal/Proc./Book: Frontiers in Physiology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

21. Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome

Anita Bálint, Klaudia Farkas, Orsolya Méhi, Bálint Kintses, Bálint Márk Vásárhelyi, Eszter Ari, Csaba Pál, Tamara Madácsy, József Maléth, Kata Judit Szántó, István Nagy, Mariann Rutka, Péter Bacsur, Diána Szűcs, Zoltán Szepes, Ferenc Nagy, Anna Fábián, Renáta Bor, Ágnes Milassin, Tamás Molnár
Journal/Proc./Book: Pharmaceuticals
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

20. Rational design of balanced dual-targeting antibiotics with limited resistance

Akos Nyerges, Tihomir Tomašič, Martina Durcik, Tamas Revesz, Petra Szili, Gabor Draskovits, Ferenc Bogar, Žiga Skok, Nace Zidar, Janez Ilaš, Anamarija Zega, Danijel Kikelj, Lejla Daruka, Balint Kintses, Balint Vasarhelyi, Imre Foldesi, Diána Kata, Martin Welin, Raymond Kimbung, Dorota Focht, Lucija Peterlin Mašič, Csaba Pal
Journal/Proc./Book: PLOS Biology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

19. Commentary on ‘Sebocyte differentiation as a new target for acne therapy: an in vivo experience’

L. Kemény, K. Szabó
Journal/Proc./Book: Journal of the European Academy of Dermatology and Venereology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

18. FTO Intronic SNP Strongly Influences Human Neck Adipocyte Browning Determined by Tissue and PPARγ Specific Regulation: A Transcriptome Analysis

Beáta B. Tóth, Rini Arianti, Abhirup Shaw, Attila Vámos, Zoltán Veréb, Szilárd Póliska, Ferenc Győry, Zsolt Bacso, László Fésüs, Endre Kristóf
Journal/Proc./Book: Cells
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

17. Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Gábor Valcz, Edit I. Buzás, Anna Sebestyén, Tibor Krenács, Zoltán Szállási, Péter Igaz, Béla Molnár
Journal/Proc./Book: Cancers
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

16. Advances in phototherapy for psoriasis and atopic dermatitis

Lajos Kemény, Emese Varga, Zoltan Novak
Journal/Proc./Book: Expert Review of Clinical Immunology
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

15. A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome

Mark Jelcic, Ke Wang, King Lam Hui, Xiao-Chuan Cai, Balázs Enyedi, Minkui Luo, Philipp Niethammer
Journal/Proc./Book: Cell Chemical Biology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

14. Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Zoltán Wiener
Journal/Proc./Book: Frontiers in Cell and Developmental Biology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

13. Periodontitis: a newly identified comorbidity in psoriasis and psoriatic arthritis

Szandra Dalmády, Lajos Kemény, Márk Antal, Rolland Gyulai
Journal/Proc./Book: Expert Review of Clinical Immunology
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

12. Cutibacterium acnes regulates the epidermal barrier properties of HPV-KER human immortalized keratinocyte cultures

Beáta Szilvia Bolla, Lilla Erdei, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Journal/Proc./Book: Scientific Reports
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

11. A Randomized Controlled Trial with a Medical Device Containing Sodium Hyaluronate and Nicotinic Acid to Increase the Efficacy of Ultraviolet Phototherapy in Psoriasis

Balázs Bende, Róbert Kui, Annamária Németh, Mariann Borsos, Zoltán Tóbiás, Gábor Erős, Lajos Kemény, Eszter Baltás
Journal/Proc./Book: Dermatology and Therapy
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

10. Intracellular Ca2+ Signalling in the Pathogenesis of Acute Pancreatitis: Recent Advances and Translational Perspectives

Petra Pallagi, Tamara Madácsy, Árpád Varga, József Maléth
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

9. Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations

Petra Szili, Gábor Draskovits, Tamás Révész, Ferenc Bogár, Dávid Balogh, Tamás Martinek, Lejla Daruka, Réka Spohn, Bálint Márk Vásárhelyi, Márton Czikkely, Bálint Kintses, Gábor Grézal, Györgyi Ferenc, Csaba Pál, Ákos Nyerges
Journal/Proc./Book: Antimicrobial Agents and Chemotherapy
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

8. The Role of P2X7 Receptor in Alzheimer’s Disease

Linda Francistiová, Carolina Bianchi, Caterina Di Lauro, Álvaro Sebastián-Serrano, Laura de Diego-García, Julianna Kobolák, András Dinnyés, Miguel Díaz-Hernández
Journal/Proc./Book: Frontiers in Molecular Neuroscience
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

7. Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?

Magdolna Szántó, Anikó Dózsa, Dóra Antal, Kornélia Szabó, Lajos Kemény, Péter Bai
Journal/Proc./Book: Experimental Dermatology
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

6. Comprehensive Proteomic Analysis Reveals Intermediate Stage of Non-Lesional Psoriatic Skin and Points out the Importance of Proteins Outside this Trend

Edit Szél, Renáta Bozó, Éva Hunyadi-Gulyás, Máté Manczinger, Kornélia Szabó, Lajos Kemény, Zsuzsanna Bata-Csörgő, Gergely Groma
Journal/Proc./Book: Scientific Reports
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

5. Cartilage Oligomeric Matrix Protein Negatively Influences Keratinocyte Proliferation Via α5β1-Integrin: Potential Relevance of Altered Cartilage Oligomeric Matrix Protein Expression in Psoriasis

Renáta Bozó, Edit Szél, Judit Danis, Barbara Gubán, Zsuzsanna Bata-Csörgő, Kornélia Szabó, Lajos Kemény, Gergely Groma
Journal/Proc./Book: Journal of Investigative Dermatology
Year: 2020
Thematic Pillar: Immuno-inflammatory Diseases

4. Unravelling the Role of Trophoblastic-Derived Extracellular Vesicles in Regulatory T Cell Differentiation

Árpád Ferenc Kovács, Nóra Fekete, Lilla Turiák, András Ács, László Kőhidai, Edit I. Buzás, Éva Pállinger
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

3. Extracellular vesicles transmit epithelial growth factor activity in the intestinal stem cell niche

Ádám Oszvald, Zsuzsanna Szvicsek, Gyöngyvér Orsolya Sándor, Andrea Kelemen, András Áron Soós, Krisztina Pálóczi, Attila Bursics, Kristóf Dede, Tamás Tölgyes, Edit I. Buzás, Anikó Zeöld, Zoltán Wiener
Journal/Proc./Book: STEM CELLS
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases

2. Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Bálint Kintses, Pramod K. Jangir, Gergely Fekete, Mónika Számel, Orsolya Méhi, Réka Spohn, Lejla Daruka, Ana Martins, Ali Hosseinnia, Alla Gagarinova, Sunyoung Kim, Sadhna Phanse, Bálint Csörgő, Ádám Györkei, Eszter Ari, Viktória Lázár, István Nagy, Mohan Babu, Csaba Pál, Balázs Papp
Journal/Proc./Book: Nature Communications
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases,Metabolic and Cardiovascular Diseases

1. Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Réka Spohn, Lejla Daruka, Viktória Lázár, Ana Martins, Fanni Vidovics, Gábor Grézal, Orsolya Méhi, Bálint Kintses, Mónika Számel, Pramod K. Jangir, Bálint Csörgő, Ádám Györkei, Zoltán Bódi, Anikó Faragó, László Bodai, Imre Földesi, Diána Kata, Gergely Maróti, Bernadett Pap, Roland Wirth, Balázs Papp, Csaba Pál
Journal/Proc./Book: Nature Communications
Year: 2019
Thematic Pillar: Immuno-inflammatory Diseases,Metabolic and Cardiovascular Diseases