ORCID ID: 0000-0003-0831-9617
Nationality: Hungarian
On the web: Group site, Twitter, Google Scholar, ResearchGate, Hungarian Doctoral Council
2016 Ph.D. – Department of Dermatology and Allergology, University of Szeged, Hungary, Supervisors: Lajos Kemény & Lóránt Lakatos; thesis
2016 Dermatologist specialization – Department of Dermatology and Allergology, University of Szeged, Hungary
2010 Medical degree („summa cum laude”)
Faculty of Medicine, University of Szeged, Hungary
2020- Mentor
Szeged Scientist Academy
2022– Principal investigator
Biological Research Centre, Szeged, Hungary
2016– Assistant professor
Department of Dermatology and Allergology, University of Szeged, Hungary
2010 – 2013 External lecturer
Department of Pathophysiology, University of Szeged, Hungary
2017 – 2020 Junior mentor
Szeged Scientist Academy
2017 – 2021 Project leader
Csaba Pál Laboratory, Biological Research Centre, Szeged, Hungary
2018 – 2021 – János Bolyai Research Fellowship
2016, 2017, 2018, 2019, 2020 – New National Excellence Program Fellowship
Between 2016 and 2021:
Two graduate students (Yoshida Mio, Sára Viemann, both wrote their theses with my supervision)
Three Szent-Györgyi students (Benjamin Papp, Anna Tácia Fülöp, Leó Asztalos)
Three Ph.D students (Balázs Koncz, Gergő Balogh, Benjamin Papp), Balázs has submitted his Ph.D. thesis in 2021
2007 – 2013 Teaching position – Pathophysiology seminars, Department of Pathophysiology, University of Szeged, Hungary
2014 – Teaching position – Dermatology practices and seminars, Department of Dermatology and Allergology, University of Szeged, Hungary
2021 – HCEMM Translational medicine course
2018 – Member of the Scientific Student Council, Faculty of Medicine, University of Szeged, Szeged, Hungary
2018 – Public body member of the Hungarian Academy of Sciences
2015 – Member, European Society for Dermatological Research
2011 – Member, Hungarian Society of Immunology
Tobias L. Lenz – HLA Promiscuity, Evolutionary Immunogenomics Research Unit, Department of Biology, University of Hamburg, Hamburg, Germany
Attila Bérces – Omixon Biocomputing Ltd., Budapest, Hungary
2020: Excellent Tutor of Scientific Student Circle at Faculty of Medicine, University of Szeged
2018: National Institute of Allergy and Infectious Diseases (NIAID) Scholarship
2017: 90th Hungarian Dermatological Society Meeting – Resdevco prize 1st place
2016: SZTE Innovation Prize 2nd place
2014: EADV Educational Grant (Bioinformatics for Skin Research Summer School)
All publications:
Total number: 16
D1: 8, Q1: 4
Citations: Google Scholar: 276 (on 2022/07/20)
First and last authored publications:
Total Number: 8
D1: 5, Q1: 1
Editorial board member of the Immunoinformatics (Elsevier) journal
Reviewer activity in: Annals of Oncology, Scientific Reports, Frontiers in Immunology, Genome, Advanced Science (reviewing 3-4 manuscripts/year)
Reviewer of the premium postdoctoral fellowship of the Hungarian Academy of Sciences.
I have developed a drug repurposing algorithm, which was applied for patenting in the U.S.
The previously neglected concept of HLA promiscuity was elaborated in detail with my leadership (Manczinger et al., PloS Biology, 2019). Also, I led the project, which discovered the role of this HLA feature in antitumor immunity (Manczinger et al., Nature Cancer, 2021). HLA promiscuity has been proved to be an accurate biomarker and we have contracted with a company in the US to work together on its application in healthcare.
We have recently published the results of another project, which focused on a provocative topic (Koncz et al., PNAS, 2021). We proposed that T cell positive selection results in a defective T cell repertoire. Consequently, overly dissimilar peptides to our own proteins are unlikely to be recognized by the immune system.
Regularly holding lectures in the Researcher’s Night Program
Holding lectures in the HiSchool career orientation program
Regularly holding lectures in the “Magyar Tudomány Ünnepe” series
Laboratory presentation for high school students (Szeged Scientist Academy activity)
Manczinger M COVID-19 and HLA: The Current State of Knowledge and Future Directions, webinar @ Omixon Academy, 2020
Manczinger M Pathogen diversity and generalist human MHC alleles. 5th Annual ISEMPH Meeting, 2019, Zürich, Switzerland
Manczinger M Pathogen Diversity Drives the Evolution of Promiscuous Peptide Binding of Human MHC-II Alleles. Keystone Symposia –Translational Systems Immunology 2018, Snowbird, USA
Manczinger M Drug Repurposing for Psoriasis – ESDR Academy for Future Leaders in Dermatology 2017, Barcelona, Spain
Manczinger M, Boross G, Papp BT, Papp B, Kemény L, Pál C: Parasite load drives rapid evolution of promiscuous peptide binding in human MHC-II alleles. One Past Health Workshop 2017, Max Planck Institute for Evolutionary Biology, Plön, Germany
Manczinger M, Kemény L: Novel factors in psoriasis pathogenesis and potential drug candidates are found with systems biology approach. Functional Genomics & Systems Biology 2013, Wellcome Trust Conference Centre, Hinxton, Cambridge, UK
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 739593. HCEMM supported by EU Programme: H2020-EU.4.a. – Teaming of excellent research institutions and low performing RDI regions. Project starting date was 1 April 2017.
