22. Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens

Mihály Koncz, Tamás Stirling, Hiba Hadj Mehdi, Orsolya Méhi, Bálint Eszenyi, András Asbóth, Gábor Apjok, Ákos Tóth, László Orosz, Bálint Márk Vásárhelyi, Eszter Ari, Lejla Daruka, Tamás Ferenc Polgár, György Schneider, Sif Aldin Zalokh, Mónika Számel, Gergely Fekete, Balázs Bohár, Karolina Nagy Varga, Ádám Visnyovszki, Edit Székely, Monica-Sorina Licker, Oana Izmendi, Carmen Costache, Ina Gajic, Bojana Lukovic, Szabolcs Molnár, Uzonka Orsolya Szőcs-Gazdi, Csilla Bozai, Marina Indreas, Katalin Kristóf, Charles Van der Henst, Anke Breine, Csaba Pál, Balázs Papp, Bálint Kintses
Journal/Proc./Book: Cell
Year: 2024
Thematic Pillar: Immuno-inflammatory Diseases

21. Widespread natural selection on metabolite levels in humans

Yanina Timasheva, Kaido Lepik, Orsolya Liska, Balázs Papp, Zoltán Kutalik
Journal/Proc./Book: Genome Research
Year: 2024
Thematic Pillar: Immuno-inflammatory Diseases

20. Phytochrome C and Low Temperature Promote the Protein Accumulation and Red-Light Signaling of Phytochrome D

Csaba Péter, Éva Ádám, Cornelia Klose, Gábor Grézal, Anita Hajdu, Gábor Steinbach, László Kozma-Bognár, Dániel Silhavy, Ferenc Nagy, András Viczián
Journal/Proc./Book: Plant And Cell Physiology
Year: 2024
Thematic Pillar: Immuno-inflammatory Diseases

19. Chloroplastic ascorbate modifies plant metabolism and may act as a metabolite signal regardless of oxidative stress

Dávid Tóth, Roland Tengölics, Fayezeh Aarabi, Anna Karlsson, André Vidal-Meireles, László Kovács, Soujanya Kuntam, Tímea Körmöczi, Alisdair R Fernie, Elton P Hudson, Balázs Papp, Szilvia Z Tóth
Journal/Proc./Book: Plant Physiology
Year: 2024
Thematic Pillar: Immuno-inflammatory Diseases

18. Interdisciplinary Analyses of Bronze Age Communities from Western Hungary Reveal Complex Population Histories

Gerber D, Szeifert B, Székely O, Egyed B, Gyuris B, Giblin JI, Horváth A, Köhler K, Kulcsár G, Kustár Á, Major I, Molnár M, Palcsu L, Szeverényi V, Fábián S, Mende BG, Bondár M, Ari E, Kiss V, Szécsényi-Nagy A.
Journal/Proc./Book: Molecular Biology and Evolution
Year: 2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

17. Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains.

Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B.
Journal/Proc./Book: Nature Microbiology
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases, Metabolic and Cardiovascular Diseases

16. Plasticity and stereotypic rewiring of the transcriptome upon bacterial evolution of antibiotic resistance.

Grézal G, Spohn R, Méhi O, Dunai A, Lázár V, Bálint B, Nagy I, Pál C, Papp B.

Journal/Proc./Book: Molecular Biology and Evolution
Year:  2023
Thematic Pillar: Immuno Inflammatory Diseases, Metabolic and Cardiovascular Diseases

15. Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan.

Correia-Melo C, Kamrad S, Tengölics R, Messner CB, Trebulle P, Townsend S, Jayasree Varma S, Freiwald A, Heineike BM, Campbell K, Herrera-Dominguez L, Kaur Aulakh S, Szyrwiel L, Yu JSL, Zelezniak A, Demichev V, Mülleder M, Papp B, Alam MT, Ralser M.
Journal/Proc./Book: Cell
Year: 2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

14. TFLink: an integrated gateway to access transcription factor-target gene interactions for multiple species.

Liska O, Bohár B, Hidas A, Korcsmáros T, Papp B, Fazekas D, Ari E.
Journal/Proc./Book: Virus Evolution
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

13. A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.

Ari E, Vásárhelyi BM, Kemenesi G, Tóth GE, Zana B, Somogyi B, Lanszki Z, Röst G, Jakab F, Papp B, Kintses B.
Journal/Proc./Book: Database
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

12. A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.

Ari E, Vásárhelyi BM, Kemenesi G, Tóth GE, Zana B, Somogyi B, Lanszki Z, Röst G, Jakab F, Papp B, Kintses B.
Journal/Proc./Book: Virus Evolution
Year: 2022
Thematic Pillar: Immuno Inflammatory Diseases, Metabolic and Cardiovascular Diseases

11. Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast

Farkas Z, Kovács K, Sarkadi Z, Kalapis D, Fekete G, Birtyik F, Ayaydin F, Molnár C, Horváth P, Pál C, Papp B.

Journal/Proc./Book: Nature Ecology and Evolution
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

10. Proteome-wide landscape of solubility limits in a bacterial cell.

Györkei Á, Daruka L, Balogh D, Őszi E, Magyar Z, Szappanos B, Fekete G, Fuxreiter M, Horváth P, Pál C, Kintses B, Papp B.
Journal/Proc./Book: Scientific reports
Year: 2022
Thematic Pillar: Immuno-inflammatory Diseases, Metabolic and Cardiovascular Diseases

9. Underground metabolism as a rich reservoir for pathway engineering.

Kovács SC, Szappanos B, Tengölics R, Notebaart RA, Papp B.
Journal/Proc./Book: Bioinformatics
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

8. Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Máté Manczinger, Balázs Koncz, Gergő Mihály Balogh, Benjamin Tamás Papp, Leó Asztalos, Lajos Kemény, Balázs Papp, Csaba Pál
Journal/Proc./Book: Nature Cancer
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

7. Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations

Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp
Journal/Proc./Book: Molecular Biology and Evolution
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

6. Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

Gábor Apjok, Gábor Boross, Ákos Nyerges, Gergely Fekete, Viktória Lázár, Balázs Papp, Csaba Pál, Bálint Csörgő
Journal/Proc./Book: Molecular Biology and Evolution
Year: 2019
Thematic Pillar: Metabolic and Cardiovascular Diseases

5. Exploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach

Viktor Vernyik, Ildikó Karcagi, Edit Tímár, István Nagy, Ádám Györkei, Balázs Papp, Zsuzsanna Györfy, György Pósfai
Journal/Proc./Book: Scientific Reports
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

4. Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

Anett Dunai, Réka Spohn, Zoltán Farkas, Viktória Lázár, Ádám Györkei, Gábor Apjok, Gábor Boross, Balázs Szappanos, Gábor Grézal, Anikó Faragó, László Bodai, Balázs Papp, Csaba Pál
Journal/Proc./Book: eLife
Year: 2019
Thematic Pillar: Metabolic and Cardiovascular Diseases

3. Unmatched level of molecular convergence among deeply divergent complex multicellular fungi

Zsolt Merényi, Arun N Prasanna, Zheng Wang, Károly Kovács, Botond Hegedüs, Balázs Bálint, Balázs Papp, Jeffrey P Townsend, László G Nagy
Journal/Proc./Book: Molecular Biology and Evolution
Year: 2019
Thematic Pillar: Metabolic and Cardiovascular Diseases

2. Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Bálint Kintses, Pramod K. Jangir, Gergely Fekete, Mónika Számel, Orsolya Méhi, Réka Spohn, Lejla Daruka, Ana Martins, Ali Hosseinnia, Alla Gagarinova, Sunyoung Kim, Sadhna Phanse, Bálint Csörgő, Ádám Györkei, Eszter Ari, Viktória Lázár, István Nagy, Mohan Babu, Csaba Pál, Balázs Papp
Journal/Proc./Book: Nature Communications
Year: 2019
Thematic Pillar: Metabolic and Cardiovascular Diseases

1. Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Réka Spohn, Lejla Daruka, Viktória Lázár, Ana Martins, Fanni Vidovics, Gábor Grézal, Orsolya Méhi, Bálint Kintses, Mónika Számel, Pramod K. Jangir, Bálint Csörgő, Ádám Györkei, Zoltán Bódi, Anikó Faragó, László Bodai, Imre Földesi, Diána Kata, Gergely Maróti, Bernadett Pap, Roland Wirth, Balázs Papp, Csaba Pál
Journal/Proc./Book: Nature Communications
Year: 2019
Thematic Pillar: Metabolic and Cardiovascular Diseases