Our immune system has to recognize and destroy pathogens and tolerate nonharmful molecules of the body. T cells – sentinels of the immune system – play a key role in this process.
Project title: Adaptive immune recognition of cancer
Immunotherapy has revolutionized cancer treatment. However, only one-third of patients respond to the treatment. As these drugs are very expensive, it is of utmost importance to identify biomarkers that can accurately predict response.
Project title: HLA promiscuity
The human immune system plays a fundamental role in killing pathogens and tumors, while it is essential to tolerate healthy cells of the human body. Tumor immunotherapy has revolutionized cancer treatment in the previous two decades.
