Human neuron physiology and therapy Core Group

Collaborations

Name of Collaborators: Prof. Michele Giugliano

Name of Institute/Company: SISSA Trieste, Italy

Project Title: Development of a realistic computational model of a human neuron.

Short Description of the Project: We develop a realistic model of a human neuron using the Neuroptimus computing environment. This model is based on electrophysiological recordings and anatomical reconstruction.

Name of Collaborators: Prof. Huib Mansvelder and Dr Natalia Goriounova

Name of Institute/Company: Vrije University, Amsterdam Netherlands

Project Title: Structural Analysis of Human Neocortex Pyramidal Cell Types.

Short Description of the Project: We quantify the microstructure of principal neuronal cell types in the human neocortex, enabling realistic computational models of their function.

Name of Collaborators: Dr Vladimir Benes

Name of Institute/Company: EMBL, Heidelberg Germany

Project Title: Transcriptomic profile of human neurons studied in brain slices obtained during surgery.

Short Description of the Project: We investigate gene expression in homologous neurons from human and mouse brain slices.

Name of Collaborators: Dr Lucia Wittner

Name of Institute/Company: Hun-Ren TTK, Budapest

Project Title: Two-photon calcium imaging of human neurons in brain slices resected during surgery.

Short Description of the Project: We study intracellular calcium transients and electrical behavior of human neurons using high-resolution imaging.

Name of Collaborators: Dr Gábor Hutóczki

Name of Institute/Company: Department of Neurosurgery, University of Debrecen

Project Title: Using human brain slices in basic and translational research.

Short Description of the Project: We use surgically resected human brain tissue for neurobiological investigations.

Name of Collaborators: Dr Attila Papp

Name of Institute/Company: Oncology Department, University of Miskolc

Project Title: Using human brain slices in basic and translational research.

Short Description of the Project: We use human brain tissue resected during surgery for collaborative translational research.

Name of Collaborators: Prof. Gábor Tamás

Name of Institute/Company: University of Szeged

Project Title: Investigating Human Brain Tissue Resected During Brain Surgery.

Short Description of the Project: We study the electrophysiological and molecular properties of neurons in resected human brain slices.

Name of Collaborators: Prof. Balázs Pál

Name of Institute/Company: University of Debrecen

Project Title: Investigating Human Brain Tissue Resected During Brain Surgery.

Short Description of the Project: We examine molecular and electrophysiological properties of neurons in human brain slices.

Name of Collaborators: Dr Miklos Erdelyi

Name of Institute/Company: University of Szeged

Project Title: Investigating Ion Channel Localization with STORM Superresolution Microscopy.

Short Description of the Project: We use dSTORM microscopy to localize ion channels in human neurons with nanometer precision.

Name of Collaborators: Dr Karolina Pircs

Name of Institute/Company: Semmelweis University, Budapest

Project Title: Parallel Investigation of Neurons in Surgically Resected Tissue and Differentiated Neurons.

Short Description of the Project: We analyze patient-derived neurons to study aging and cellular function.

Name of Collaborators: Dr Balazs Bende

Name of Institute/Company: HCEMM

Project Title: Organizing investigation and collaboration services with human brain tissue.

Short Description of the Project: We coordinate collaborations with partners and manage administrative and legal activities.

Name of Collaborators: Dr Tibor Pankotai

Name of Institute/Company: HCEMM

Project Title: Neuron and slice culturing, and genomic expression analysis.

Short Description of the Project: We culture human brain tissue and develop organoids; we collaborate with industrial partners.

Name of Collaborators: Dr Lőrinc Pongor

Name of Institute/Company: HCEMM

Project Title: Electrophysiology and pharmacology of cancer cells.

Short Description of the Project: We study ion channels in tumor cells to understand cancer progression.

Name of Collaborators: Dr Lőrinc Pongor and Mr Kolos Nemes

Name of Institute/Company: HCEMM

Project Title: Artificial intelligence-operated analysis of brain tissue microstructures.

Short Description of the Project: We develop AI-assisted analysis tools for human brain tissue microstructures.

Name of Collaborators: Dr Ferhan Ayaydin

Name of Institute/Company: HCEMM

Project Title: High-resolution fluorescence imaging of brain tissue.

Short Description of the Project: We investigate immunofluorescence reactions using high-resolution confocal microscopy.

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