Modifying pigmentation in melanocytes by minimizing UV radiation
Modulation of UV response in keratinocytes to modify pigment producing factors
Identification of regulators of ferroptotic cell death in melanoma
Predicting genetic vulnerability and pharmacologic compound sensitivity of melanoma subsets defined by proteogenomics
Overcoming resistance to immune-checkpoint blockade in a novel mouse model of melanoma
Investigating the efficacy and safety of the combination of targeted and immune-based therapies in human melanoma
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 739593. HCEMM supported by EU Programme: H2020-EU.4.a. – Teaming of excellent research institutions and low performing RDI regions. Project starting date was 1 April 2017.