29. Inflammasome Activity in the Skeletal Muscle and Heart of Rodent Models for Duchenne Muscular Dystrophy. Int J Mol Sci. 2023 May 9;24(10):8497.

Onódi Z, Szabó PL, Kucsera D, Pokreisz P, Dostal C, Hilber K, Oudit GY, Podesser BK, Ferdinandy P, Varga ZV, Kiss A.
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

28. BRAF RNA is prognostic and widely expressed in lung adenocarcinoma.

Dora D, Vörös I, Varga ZV, Takacs P, Teglasi V, Moldvay J, Lohinai Z.
Journal/Proc./Book: Translational Lung Cancer Research
Year:  2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

27. Cardioprotective efficacy of limb remote ischemic preconditioning in rats: discrepancy between meta-analysis and a three-centre in vivo study.

Sayour NV, Brenner GB, Makkos A, Kiss B, Kovácsházi C, Gergely TG, Aukrust SG, Tian H, Zenkl V, Gömöri K, Szabados T, Bencsik P, Heinen A, Schulz R, Baxter GF, Zuurbier CJ, Vokó Z, Ferdinandy P, Giricz Z.

Journal/Proc./Book: Caridovascular Research
Year:  2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

26. Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling.

Schoger E, Bleckwedel F, Germena G, Rocha C, Tucholla P, Sobitov I, Möbius W, Sitte M, Lenz C, Samak M, Hinkel R, Varga ZV, Giricz Z, Salinas G, Gross JC, Zelarayán LC.

Journal/Proc./Book: Communications Biology
Year:  2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

25. IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH.

Kucsera D, Tóth VE, Sayour NV, Kovács T, Gergely TG, Ruppert M, Radovits T, Fábián A, Kovács A, Merkely B, Ferdinandy P, Varga ZV.
Journal/Proc./Book: Scientific Reports
Year: 2023
Thematic Pillar: Metabolic and Cardiovascular Diseases

24. New targets and indications for probenecid

Onódi Z, Koch S, Rubinstein J, Ferdinandy P, Varga ZV.
Journal/Proc./Book: British Journal of Pharmacology
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

23. Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.

Gergely TG, Kucsera D, Tóth VE, Kovács T, Sayour NV, Drobni ZD, Ruppert M, Petrovich B, Ágg B, Onódi Z, Fekete N, Pállinger É, Buzás EI, Yousif LI, Meijers WC, Radovits T, Merkely B, Ferdinandy P, Varga ZV.
Journal/Proc./Book: British Journal of Pharmacology
Year: 2022

22. Saxagliptin Cardiotoxicity in Chronic Heart Failure: The Role of DPP4 in the Regulation of Neuropeptide Tone.

Vörös I, Onódi Z, Tóth VÉ, Gergely TG, Sághy É, Görbe A, Kemény Á, Leszek P, Helyes Z, Ferdinandy P, Varga ZV.

Journal/Proc./Book: Biomedicines
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

21. Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.

Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Honer M, Fingerle J, Scheffel J, Broichhagen J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, Ullmer C, McCormick PJ, Oddi S, Spaink HP, Maccarrone M, Veprintsev DB, Carreira EM, Grether U, Nazaré M.

Journal/Proc./Book: Chemical Science
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

20. Inflammasome activation in end-stage heart failure-associated atrial fibrillation.

Kugler S, Onódi Z, Ruppert M, Sayour AA, Oláh A, Benke K, Ferdinandy P, Merkely B, Radovits T, Varga ZV.

Journal/Proc./Book: ESC Heart Failure
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

19. PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients.

Szabó D, Sárszegi Z, Polgár B, Sághy É, Reglődi D, Tóth T, Onódi Z, Leszek P, Varga ZV, Helyes Z, Kemény Á, Ferdinandy P, Tamás A.
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2022
Thematic Pillar: Metabolic and Cardiovascular Diseases

18. Interplay of Oxidative Stress and Necrosis-like Cell Death in Cardiac Ischemia/Reperfusion Injury: A Focus on Necroptosis.

Adameova A, Horvath C, Abdul-Ghani S, Varga ZV, Suleiman MS, Dhalla NS.
Journal/Proc./Book: Biomedicines
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

17. Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype. J Mol Cell Cardiol.

Onódi Z, Visnovitz T, Kiss B, Hambalkó S, Koncz A, Ágg B, Váradi B, Tóth VÉ, Nagy RN, Gergely TG, Gergő D, Makkos A, Pelyhe C, Varga N, Reé D, Apáti Á, Leszek P, Kovács T, Nagy N, Ferdinandy P, Buzás EI, Görbe A, Giricz Z, Varga ZV.
Journal/Proc./Book: Journal of Molecular and Cellular Cardiology
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

16. Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection

Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B. Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V. Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy
Journal/Proc./Book: Frontiers in Pharmacology
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

15. Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs

András Makkos, Bence Ágg, Zoltán V. Varga, Zoltán Giricz, Mariann Gyöngyösi, Dominika Lukovic, Rainer Schulz, Monika Barteková, Anikó Görbe, Péter Ferdinandy
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

14. Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice

Beáta Róka, Pál Tod, Tamás Kaucsár, Éva Nóra Bukosza, Imre Vörös, Zoltán V. Varga, Balázs Petrovich, Bence Ágg, Péter Ferdinandy, Gábor Szénási, Péter Hamar
Journal/Proc./Book: Biomedicines
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

13. Evidence of a Myenteric Plexus Barrier and its Macrophage-Dependent Degradation during Murine Colitis: Implications in Enteric Neuroinflammation

David Dora, Szilamer Ferenczi, Rhian Stavely, Viktoria E. Toth, Zoltan V. Varga, Tamas Kovacs, Ildiko Bodi, Ryo Hotta, Krisztina J. Kovacs, Allan M. Goldstein, Nandor Nagy
Journal/Proc./Book: Cellular and Molecular Gastroenterology and Hepatology
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

12. Systematic review and network analysis of microRNAs involved in cardioprotection against myocardial ischemia/reperfusion injury and infarction: Involvement of redox signalling

András Makkos, Bence Ágg, Balázs Petrovich, Zoltán V. Varga, Anikó Görbe, Péter Ferdinandy
Journal/Proc./Book: Free Radical Biology and Medicine
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

11. AIM2-driven inflammasome activation in heart failure

Zsófia Onódi, Mihály Ruppert, Dániel Kucsera, Alex Ali Sayour, Viktória E Tóth, Gábor Koncsos, Julianna Novák, Gábor B Brenner, András Makkos, Tamás Baranyai, Zoltán Giricz, Anikó Görbe, Przemyslaw Leszek, Mariann Gyöngyösi, Iván G Horváth, Rainer Schulz, Béla Merkely, Péter Ferdinandy, Tamás Radovits, Zoltán V Varga
Journal/Proc./Book: Cardiovascular Research
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

10. Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity

Attila Oláh, Bálint András Barta, Alex Ali Sayour, Mihály Ruppert, Eszter Virág-Tulassay, Julianna Novák, Zoltán V. Varga, Péter Ferdinandy, Béla Merkely, Tamás Radovits
Journal/Proc./Book: Antioxidants
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

9. Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice

Dániel Kucsera, Viktória E. Tóth, Dorottya Gergő, Imre Vörös, Zsófia Onódi, Anikó Görbe, Péter Ferdinandy, Zoltán V. Varga
Journal/Proc./Book: Frontiers in Physiology
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

8. Influence of cardiometabolic comorbidities on myocardial function, infarction, and CARDIOPROTECTION: Role of cardiac redox signaling

Ioanna Andreadou, Andreas Daiber, Gary F. Baxter, Maria.Felice Brizzi, Fabio di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán.V. Varga, Coert Zuurbier, Rainer Schulz, Péter Ferdinandy
Journal/Proc./Book: Free Radical Biology and Medicine
Year: 2021
Thematic Pillar: Metabolic and Cardiovascular Diseases

7. PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation

Ioanna Andreadou, Maria Tsoumani, Gemma Vilahur, Ignatios Ikonomidis, Lina Badimon, Zoltán V. Varga, Péter Ferdinandy, Rainer Schulz
Journal/Proc./Book: Frontiers in Physiology
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

6. Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains

Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V. Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinandy, István M. Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

5. Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells

Roman C. Sarott, Matthias V. Westphal, Patrick Pfaff, Claudia Korn, David A. Sykes, Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Marie Weise, Yelena Mostinski, Pattarin Hompluem, Eline Koers, Tamara Miljuš, Nicolas J. Roth, Hermon Asmelash, Man C. Vong, Jacopo Piovesan, Wolfgang Guba, Arne C. Rufer, Eric A. Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A. Zirwes, Anja Osterwald, Anto Pavlovic, Svenja Moes, Jennifer Beck, Irene Benito-Cuesta, Teresa Grande, Samuel Ruiz de Martı́n Esteban, Alexei Yeliseev, Faye Drawnel, Gabriella Widmer, Daniela Holzer, Tom van der Wel, Harpreet Mandhair, Cheng-Yin Yuan, William R. Drobyski, Yurii Saroz, Natasha Grimsey, Michael Honer, Jürgen Fingerle, Klaus Gawrisch, Julian Romero, Cecilia J. Hillard, Zoltan V. Varga, Mario van der Stelt, Pal Pacher, Jürg Gertsch, Peter J. McCormick, Christoph Ullmer, Sergio Oddi, Mauro Maccarrone, Dmitry B. Veprintsev, Marc Nazaré, Uwe Grether, Erick M. Carreira
Journal/Proc./Book: Journal of the American Chemical Society
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

4. Anti-PD-1 Therapy Does Not Influence Hearing Ability in the Most Sensitive Frequency Range, but Mitigates Outer Hair Cell Loss in the Basal Cochlear Region

Judit Szepesy, Gabriella Miklós, János Farkas, Dániel Kucsera, Zoltán Giricz, Anita Gáborján, Gábor Polony, Ágnes Szirmai, László Tamás, László Köles, Zoltán V. Varga, Tibor Zelles
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

3. Chronic treatment with rofecoxib but not ischemic preconditioning of the myocardium ameliorates early intestinal damage following cardiac ischemia/reperfusion injury in rats

Szilvia B. László, Bernadette Lázár, Gábor B. Brenner, András Makkos, Mihály Balogh, Mahmoud Al-Khrasani, Barbara Hutka, Amir Mohammadzadeh, Ágnes Kemény, Terézia László, Bálint Scheich, Tamara Szabados, Éva Kenyeres, Zoltán Giricz, Péter Bencsik, Zoltán V. Varga, Julianna Novák, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori
Journal/Proc./Book: Biochemical Pharmacology
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

2. Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes

Éva Sághy, Imre Vörös, Bence Ágg, Bernadett Kiss, Gábor Koncsos, Zoltán V. Varga, Anikó Görbe, Zoltán Giricz, Rainer Schulz, Péter Ferdinandy
Journal/Proc./Book: International Journal of Molecular Sciences
Year: 2020
Thematic Pillar: Metabolic and Cardiovascular Diseases

1. Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system

Annelot C.M. van Esbroeck, Zoltan V. Varga, Xinyu Di, Eva J. van Rooden, Viktória E. Tóth, Zsófia Onódi, Mariusz Kuśmierczyk, Przemyslaw Leszek, Péter Ferdinandy, Thomas Hankemeier, Mario van der Stelt, Pál Pacher
Journal/Proc./Book: Pharmacological Research
Year: 2019
Thematic Pillar: Metabolic and Cardiovascular Diseases