HCEMM-USZ StemCell Research Group

Group Leader

András Dinnyés

Group Leader

Current positions

2005- General Director of BioTalentum Ltd., Gödöllő HUNGARY
2008- Full Professor, Szent István University, Head of Molecular Animal Biotechnology Laboratory
2018- Head of Pluripotent Stem Cell Technology Platform; Institute for Translational Biomedicine, University of Szeged
2019- Honorary Professor; Sichuan University; Chengdu, China

Research interests

  • Human, mouse and rabbit iPSC generation
  • 2D and 3D differentiation of patient-specific iPSC-derived neuronal, cardia, beta and other cell types
  • The development of novel human cellular systems and animal models for biomedical research, regenerative medicine and drug testing and to provide technical services for the pharmaceutical/medical industry

Ongoing projects

  • FP7: 17 projects, in 9 as scientific coordinator
  • H2020: 11 projects, in 2 as scientific coordinator

Education and selection of relevant previous positions:

1995 PhD in Veterinary Sciences, Hungarian Academy of Sciences, HU
2002 DSc Animal Biotechnology, Hungarian Academy of Sciences, HU
1991-1992 Fulbright Scholarship, National Zoo, Smithsonian Inst., Washington D.C., USA
1994-1997 Research Fellow; Head of the Embryology Laboratory, Agricultural Biotechnology Centre, Hungary
1997-1999 Visiting Research Scientist, Dep. of Animal Science, University of Connecticut, USA
2000-2001 Nuclear Transfer Team Leader, Dept. Gene Expression and Development, Roslin Institute BBSRC, Roslin, UK
2003-2006 Invited Professor, Head, Hungarian Academy of Sciences and Szt. Istvan University, Research Group for Applied Animal Genetics and Biotechnology, Gödöllö, Hungary
2003-2008 Scientific Advisor, Team leader, Agricultural Biotechnology Center, Genetic Reprogramming Team, Gödöllö, Hungary
2008-2009 F.C. Donders Chair Professor, Veterinary Sciences Faculty, Utrecht University, Utrecht, The Netherlands
2010-2016 Full Professor (0.2 FTE) Department of Animal Health, Veterinary Sciences Faculty, Utrecht University, Utrecht, The Netherlands

Student supervision:

Has supervised 20 PhDs and 60 Postdoctoral researchers

Awards and Honors:

1989 Gold Medal „Pro Scientia”
2013 “Denis Gabor” Innovation Award
2018 Member of the Academia Europaea

Selected Administrative responsibilities

1992- International Embryo Transfer Society, USA, member (Governor 2008-2010)
2008-2012 Member of the EFSA advisory committee on cloning
2008- Elected Member of the Board of the Hungarian Biotechnology Association
2015- Elected Member of the Board of Hungarian Innovation Society
2010- Human Reproduction Committee, Health Scientific Council, Ministry of Health
2012- Member of the Hungarian Academy of Sciences, Committee on Animal Experimentations (vice-chair of the Committee from 2018)
2014- Member of the Scientific Advisory Board, Food Science Research Institute, National Agricultural Research and Innovation Centre, Budapest, Hungary

Scientific activities:

>200 publications with >6500 citations. Total IF: >500, h-Index: 41

Publications

2020:

  1. Julianna Kobolak, Annamaria Teglasi, Tamas Bellak, Zofia Janstova, Kinga Molnar, Melinda Zana, Istvan Bock, Lajos Laszlo, Andras Dinnyes Human induced pluripotent stem cell- derived 3D neurospheres are suitable for neurotoxicity screening (Cells 2020, 9, 1122; doi:10.3390/cells9051122)

2019:

  1. JOURNAL OF ALZHEIMER’S DISEASE 72 : 3 pp. 885-899. , 15 p. (2019)

2017:

  1. Schmidt, ZB ; Lehmann, M ; Gutbier, S ; Nembo, E ; Noel, S ; Smirnova, L ; Forsby, A ; Hescheler, J ; Avci, XH ; Hartung, T et al.
    ARCHIVES OF TOXICOLOGY 91 : 1 pp. 1-33. , 33 p. (2017)
  2. Takacs, E ; Boto, P ; Emilia, Simo ; Csuth, TI ; Toth, BM ; Raveh-Amit, H ; Pap, A ; Kovács, EG ; Kobolak, J ; Benkö, S et al.
    JOURNAL OF IMMUNOLOGY 198 : 1 pp. 239-248. , 10 p. (2017)

2016:

  1. Chandrasekaran, A ; Avci, XH ; Leist, M ; Kobolák, J ; Dinnyés, A
    FRONTIERS IN CELLULAR NEUROSCIENCE 10 pp. 1-27. , 27 p. (2016)
  2. Zhou, S ; Ochalek, A ; Szczesna, K ; Avci, HX ; Kobolák, J ; Varga, E ; Rasmussen, M ; Holst, B ; Cirera, S ; Hyttel, P et al.
    DIFFERENTIATION 92 : 4 pp. 183-194. , 12 p. (2016)

2014:

  1. Klincumhom, N ; Tharasanit, T ; Thongkittidilok, C ; Tiptanavattana, N ; Rungarunlert, S ; Dinnyes, A ; Techakumphu, M
    NEUROSCIENCE LETTERS 578 pp. 1-6. , 6 p. (2014)
  2. Varga, E ; Nemes, C ; Davis, RP ; Ujhelly, O ; Klincumhom, N ; Polgar, Z ; Muertthaisong, S ; Pirity, MK ; Dinnyes, A
    EXPERIMENTAL CELL RESEARCH 322 : 2 pp. 335-344. , 10 p. (2014)
  3. CELL DEATH AND DIFFERENTIATION 21 : 4 pp. 547-556. , 10 p. (2014)

2002:

  1. Dinnyés, A ; de Sousa, PA ; King, T ; Wilmut, I
    CLONING AND STEM CELLS 4 : 1 pp. 81-90. , 10 p. (2002)

2001:

  1. Denning, C ; Burl, S ; Ainslie, A ; Bracken, J ; Dinnyes, A ; Fletcher, J ; King, T ; Ritchie, M ; Ritchie, WA ; Rollo, M et al.
    NATURE BIOTECHNOLOGY 19 : 6 pp. 559-562. , 4 p. (2001)

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